Using NMR parameters for the configurational and conformational study of the 3,4-dihydro-2H-pyrrol-2-alkyl carboxylates and that of their acyclic and cyclic precursors diesters (Utilisation des parametres de RMN XH pour lʹetude configurationnelle et confo

In this article, we will present a stereochemical study of 3 types of compounds: The acyclic diesters derived from the diethyl acetamidomalonate 1, the cyclic diesters derived from the diethyl of 3.4-dihydro-5-phenyl-2H-pyrrole-2.2-dicarboxylate 2, the methyl esters derived from 3.4-dihydro-2H-pyrrole-2-carboxylate 3. These compounds were prepared during our work and engaged in dipolar-1.3 cycloaddition on different symmetric dipolarophiles [1, 2]. In order to characterize and confirm the stereochemistry of these molecules, we used the :H NMR parameters and DREIDING models.