Title of article
Direction control in DNA binding of chiral D-lysine-based peptide nucleic acid (PNA) probed by electrospray mass spectrometry
Author/Authors
Sforza، Stefano نويسنده , , Tedeschi، Tullia نويسنده , , Corradini، Roberto نويسنده , , Dossena، Arnaldo نويسنده , , Marchelli، Rosangela نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
-1101
From page
1102
To page
0
Abstract
The DNA binding abilities of peptide nucleic acids (PNAs), both achiral and bearing three adjacent D-lysine-based monomers in the middle of the strand (chiral box PNA), were studied by means of electrospray mass spectrometry (ESI-MS). In contrast with achiral PNA, Chiral box PNA was confirmed to exert high direction control (antiparallel vs. parallel DNA target) in DNA binding.
Keywords
unitary group , general linear group , linear map
Journal title
CHEMICAL COMMUNICATIONS - LETCHWORTH
Serial Year
2003
Journal title
CHEMICAL COMMUNICATIONS - LETCHWORTH
Record number
68528
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