Incidence of early Left Ventricular thrombus and stroke after acute Myocardial Infarction in the Primary coronary Intervention era compared to conservative treatment

Background: Left ventricular thrombus is a well known complication of acute myo¬cardial infarction. There are different data according to incidence of left ventricular thrombus in relation to the treatment of acute myocardial infarction. Objectives: The aim of this study was to further clarify theadvantages of one or the other method related to complications after acute myo- cardial infarction. Methods: This study was approved by the Committee of Ethics. Writ¬ten informed consent was obtained from the patients prior to enrolment. This was prospective study performed in two different cardiologic centers in the same city, with dif¬ferent possibilities to treat acute myocardial infarction; one conservatively and another invasively. Four hundred consecutive pa¬tients with ST elevation acute myocardial infarction were accepted in the study dur¬ing 2010. (200 patients per each center) respectively. Structural index, mean average, standard deviation, t-test and Chi2 were derived by SigmaStat and SPSS program. Results: No significant demographic data differenceswere found between two groups. Incidence of LVT were in PCI group 2% and 25% in non-PCI group, with significant difference (p<0.0003). No patients with ischemic stroke were recorded in PCI group and 4% were found with strokes in non-PCI group or 16% in those with left ventricular thrombus of non-PCI group. Conclusions: PCI treatment is highly effective in reduc¬ing left ventricular thrombus compared to non-PCI treatment. Our data are in favor of aggressive treatment of acute myocardial infarction, resulting in fewer left ventricular thrombus and strokes.