Serum and Stimulated Saliva 25-hydroxy Vitamin D in Menopausal Women with Xerostomia

Aim: The aim of this study was to evaluate serum and stimulated whole saliva 25-hydroxy vitamin D (25-(OH)D) levels in women with/without oral dryness (OD) feeling. Methods and materials: A case-control study was carried out in 91 selected menopausal women aged 47 - 77 years with or without OD feeling (45 as case and 46 as control) conducted at the Clinic of Oral Medicine, Tehran university of medical sciences. Paraffin-stimulated saliva samples were obtained by expectoration. The serum and saliva 25-(OH)D concentrations were measured by ELISA. Statistical analysis of Studentʹs t-test was used. Results: No significant difference was found in serum and stimulated whole saliva 25-(OH)D concentrations between the two groups. Conclusions: It seems that there is no relationship between OD feeling and stimulated whole saliva or serum 25-(OH) D in menopausal women.