Spatially controlled self-assembly of gold nanoparticles encased in (alpha)-helical polypeptide nanospheres

Gold nanoparticles (Au–NPs) are encased in aqueous nanospheres of (alpha)-helical poly((gamma)-benzyl L-glutamate)s (PBLG, number average degree of polymerization: n= 32), with spatially controlled self-assembly structures of solid core–shell nanospheres or double-layered hollow nanocapsules.