A facile synthesis of novel cyclodextrin derivatives incorporating one (beta)-(1,4)-glucosidic bond and their unique inclusion ability

Novel cyclodextrin derivatives incorporating one (beta)-(1,4)-glucosidic bond are easily synthesized in three steps from permethylated (alpha)and (beta)-cyclodextrins, and such host molecules show inclusion selectivity for sodium m-nitrobenzoate over the corresponding p-isomer, in contrast to the cases of the parent permethylated (alpha)- and (beta)-cyclodextrins.