Title of article :
Functionalized LNA (locked nucleic acid): high-affinity hybridization of oligonucleotides containing N-acylated and N-alkylated 2-amino-LNA monomers
Author/Authors :
Wengel، Jesper نويسنده , , S?rensen، Mads D. نويسنده , , Petersen، Michael نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2003
Abstract :
A molecular dynamics (MD) simulation, synthesis and very efficient hybridization for a series of N-acylated and N-alkylated derivatives of 2ʹamino-LNA are reported.
Keywords :
Goodness of fit , Identifiability , Model diagnosis , Parametric bootstrap , Restricted latent class models
Journal title :
CHEMICAL COMMUNICATIONS - LETCHWORTH
Journal title :
CHEMICAL COMMUNICATIONS - LETCHWORTH
