Author/Authors :
مقصودلو، ملك طاهر نويسنده دانشگاه سيستان و بلوچستان , , حاضري، نورالله نويسنده دانشگاه سيستان و بلوچستان , , حبيبي خراساني، سيد مصطفي نويسنده Habibi-Khorassani, Sayyed Mostafa , مرندي، قاسم نويسنده , , مراديان، مجيد نويسنده , , سليماني رودي، وحيده نويسنده ,
Abstract :
The 1:1 adduct intermediate of alkyl or aryl isocyanides and dialkyl acetylenedicarboxylates were protonated by acetic acid to produce dialkyl-2-[N-acetyl-N-(alkyl or aryl)carbamoyl]butandioate derivatives and dynamic 1H NMR effects were observed in these compounds. The calculated free-energy of activation (?G?) for restricted rotation around the aryl-nitrogen single bonds in dimethyl-2-[N-acetyl-N-(2, 6-dimethyphenyl)carbamoyl]butandioate (3d) amounts to 58.2 ± 2 kJ.mol-1 with first order rate constant (k=189.3 s-1) at appropriate temperature.
