An unexpected and novel synthesis of pyrrole derivatives via isocyanide-based multicomponent reactions

The 1:1 intermediate, generated by the addition of cyclohexyl isocyanide to dialkyl acetylenedicarboxylates was trapped by cyclohexyl isocyanate in a one-pot three-component reaction to give alkyl 1-cyclohexyl-4-(cyclohexylcarbamoyl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carboxylate derivatives in good yields without using any catalyst and activation..