Electrochemical Behavior and Determination of Cilostazol in Pure, Urine and in Pharmaceutical Formulations

The adsorptive and electrochemical oxidation behavior of Cilostazol has been studied at CPE and GCE in Britton - Robinson (BR) (pH 2.0 to 12.0). The anodic oxidation at 663 and 682 mV for CPE and GCE respectively. Differential pulse voltammetry was used to determine Cilostazol in the pure and in pharmaceutical formulations. The linear calibration was obtained from: 4.0×10-7–6.40×10-6 M and 5×10-7–8.7×10-6 M for carbon past and glassy carbon electrode. The percentage recoveries were found in the ranges: 99.50-100.80%, 99.20 -100.10% at carbon past and glassy carbon electrodes, respectively. The RSD for five measurements were found in the ranges: 0.403-0.742% and 0.657-0.84 %,. The method was applied to determine Cilostazol has in dilute urine sample and dosage forms and compared with official methods.