Author/Authors :
Rahzani، Kobra نويسنده Department of Nursing, Arak University of Medical Sciences, Arak,I ran , , Malekirad، Ali Akbar نويسنده Department of Biology, Payame Noor University, Iran , , Zeraatpishe، Akbar نويسنده Department of Biology, Jiroft Branch, Islamic Azad University, Jiroft, Iran , , Hosseini، Naser نويسنده Department of Medicinal Plants, Faculty of Agriculture and Natural Resources, Arak University, Arak, Iran , , Seify، Seyed Mohammad Reza نويسنده , , Abdollahi، Mohammad نويسنده ,
Abstract :
Medicinal plants are presumed to be natural sources of antioxidants that protect organisms
from oxidative stresses. The present investigation aims to study the anti-oxidative stress activity of the Stachys lavandulifolia (S. lavandulifolia) plant. This trial was conducted
on 26 healthy human subjects. The study was done in a before after fashion. The included subjects were asked to consume the prepared infusion from 3 g aerial parts of S. lavandulifolia on a daily basis. Doses were administered in every morning and evening for 14 days. At the beginning and the end of the study, blood samples were acquired to determine
the level of cellular lipid peroxidation and the total content of serum antioxidants. Biomarkers analyzed from samples obtained before start of treatment and 14 days post treatment, were subjected to paired t test analysis. Total blood antioxidants
increased and reached from 2.3 ± 0.84 ?mol/ml to 3.3 ± 0.54 ?mol/ml. The lipid peroxidation reduced and reached from 8.38 ± 1.78 to 11.6 ± 2.64 nmol/ml. The results suggest that S. lavandulifolia
possesses marked anti-oxidative stress activity and it can be useful as a supplement
in the management of diseases related to oxidative stress (Registration Number: IRCT2013012210003N2).
