Author/Authors :
Hollweck، Trixi Trixi نويسنده Department of Cardiac Surgery, Munich University Medical Center, Munich, Germany Hollweck, Trixi Trixi , Hagl، Christian Christian نويسنده Department of Cardiac Surgery, Munich University Medical Center, Munich, Germany Hagl, Christian Christian , Eissner، Günther Eissner Günther نويسنده Department of Cardiac Surgery, Munich University Medical Center, Munich, Germany Eissner, Günther Günther
Abstract :
Heart failure is one of the leading causes of death worldwide. End stage disease often requires heart
transplantation, which is hampered by donor organ shortage. Tissue engineering represents a promising
alternative approach for cardiac repair. For the generation of artificial heart muscle tissue several cell types,
scaffold materials and bioreactor designs are under investigation. In this review, the use of mesenchymal stem
cells derived from human umbilical cord tissue (UCMSC) for cardiac tissue engineering will be discussed.