Quinine/selectfluor combination induced asymmetric semipinacol rearrangement of allylic alcohols: an effective and enantioselective approach to (alpha)-quaternary (beta)-fluoro aldehydes

A quinine/Selectfluor combination inducing rearrangement reaction of allylic alcohols was discovered, which involved a moderate yield with good enantioselective construction of (alpha)-quaternary carbon center and (beta)-fluoro aldehyde under base condition.