Controlling diastereoselectivity in the reactions of enantiomerically pure (alpha)-bromoacyl-imidazolidinones with nitrogen nucleophiles: substitution reactions with retention or inversion of configuration

Diastereoselective substitution reactions of (alpha)-bromoacyl-imidazolidinones with nitrogen nucleophiles can be promoted with either retention or inversion of configuration by carrying out reactions under epimerising or non-epimerising conditions.