Abstract :
An assessment is offered of the recent debate on information in the philosophy of
biology, and an analysis is provided of the notion of information as applied in scientific
practice in molecular genetics. In particular, this paper deals with the dependence of
basic generalizations of molecular biology, above all the ‘central dogma’, on the socalled
‘informational talk’ (Maynard Smith [2000a]). It is argued that talk of information
in the ‘central dogma’ can be reduced to causal claims. In that respect, the primary aim
of the paper is to consider a solution to the major difficulty of the causal interpretation
of genetic information: how to distinguish the privileged causal role assigned to nucleic
acids, DNA in particular, in the processes of replication and protein production. A
close reading is proposed of Francis H. C. Crick’s On Protein Synthesis ([1958]) and
related works, to which we owe the first explicit definition of information within the
scientific practice of molecular biology.
