Title of article :
Enantioselective organocatalytic Michael addition of malonate esters to nitro olefins using bifunctional cinchonine derivatives
Author/Authors :
Dixon، Darren J. نويسنده , , Ye، Jinxing نويسنده , , Hynes، Peter S. نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
A family of 9-amino(9-deoxy) epicinchonine derivatives, possessing a range of mono- and bidentate hydrogen bond donor groups at the 9-position, were synthesised and evaluated for asymmetric organocatalytic activity in the dimethyl malonate Michael addition to (beta)nitrostyrene; thiourea derivative 1e was identified as the most effective bifunctional organic catalyst and found to induce high enantioselectivity in the malonate ester Michael addition reaction to a range of nitro olefins.
Keywords :
Fenton-like , Oxidation , H2O2 , Carbon-Fe catalysts , Orange II
Journal title :
CHEMICAL COMMUNICATIONS - LETCHWORTH
Journal title :
CHEMICAL COMMUNICATIONS - LETCHWORTH