Abstract :
Aims: The antimicrobial activities of the leaf extract of Moringa oleifera on certain enteropathogenic and orthopaedics’
wounds bacteria and fungi were investigated. Its phytochemical constituents and nutritional potentials were as well
assessed.
Methodology and results: The antimicrobial activities of the leaf extracts were evaluated using paper disc diffusion
method. All the leaf extracts showed little inhibitory effect on the enteropathogens, whereas aqueous and methanolic
extracts showed appreciable inhibitory effects on the orthopaedic’s wounds bacteria at 30mg/ml. Ethanolic extract did
not show any zone of growth inhibition on the wound bacteria. All the fungal organisms except Aspergillus flavus were
resistant to both aqueous and methanolic extracts of the leaf, meanwhile Ethanolic extract showed appreciable inhibitory
effect on Tricophyton mentagrophyte, Pullarium sp, Aspergilus flavus and Penicillium sp. Minimum inhibitory
concentration was 20mg/ml on all the enteropathogens and ranged from 3.75 to 30 < g/ml on the orthopaedics’ wounds
organisms. Phytochemical analysis revealed less than 1 % of alkaloids, tannin, flavonoids and phenol in the leaf and
contained appreciable quantity of calcium, magnesium, iron and 45.4 % carbohydrate, 16.2 % protein and 9.68 % fibre.
Conclusion, significance and impact of study: The study showed that Moringa oleifera leaves possess inhibitory
properties thus can serve as an alternative therapy for wounds and certain fungal infections and also a good source of
nutrient supplements.
