Preparation of Hexakis(6-O-mesitylsulfonyl)cyclomaltooctaoses and Structural Validation of the Four Isomers Using Heteronuclear Multiple Bond Correlation Spectroscopy

Four cyclomaltooctaose derivatives 1a-d, which possess six mesitylsulfonyloxy groups on their C(6) atoms, were prepared. The assignment of the regiosiomers was performed by observing the long-range coupling through a glycoside linkage between H(1ʹ) -C(4) and C(1ʹ) -H(4) using a heteronuclear multiple-bond correlation (HMBC) method.