Plant Monooxygenases: Participation in Xenobiotic Oxidation

The induction of individual components of the plant microsomal monooxygenase system have been studied. Quantitative distribution of NADPH reducible equivalents at monooxygenase and oxidase reactions and rereduction of coenzyme have been exhibited when there is deficiency of oxygen. Xenobiotic oxidation specificity in NADPH and NADH synergism with NADPH have been detected. The dependence of hydroxilation rate on the degree of hydrophobicity of xenobiotic molecules has been established. The possibility of cytochrome P-450 switching over from biosynthetic into detoxication pathway and transformation of monooxigenase mechanism of oxidation into peroxidase according to plant age have been demonstrated.