Author/Authors :
Khazdooz، Leila نويسنده , , Zarei، Amin نويسنده , , Hajipour، Abdol R نويسنده Dept. of Pharmacology, University of Wisconsin, Medical School, Madison, 53706-1532, WI, USA , , Sheikhan، Nafisehsadat نويسنده ,
Abstract :
An efficient, mild and environmentally friendly method was developed for the Strecker reaction to synthesize ?-aminonitriles in the presence of methyl imidazolium hydrogen sulfate ([Hmim][HSO4]) as an efficient catalyst. These syntheses were performed via a one-pot three-component condensation of aldehydes (or ketones), amines, and trimethylsilyl cyanide under mild and solvent free conditions
