Accumulation and excretion of diazinon, fenthion and fenitrothion by killifish: Comparison of individual and mixed pesticides

A study was made of differences in the accumulation and excretion of diazinon, fenthion and fenitrothion by killifish (Oryzias latipes) between experiments with individual and mixed pesticides. The bioconcentration factor (BCF) of the pesticides in the former reached plateau levels less rapidly than that in the latter. There was little difference in the BCF and excretion rate constants of the pesticides between the experiments. It was concluded that the accumulation and excretion of pesticides present in mixtures can be evaluated by data for the individual pesticides.