• Title of article

    Quasispecies and recombination

  • Author/Authors

    Martin Nilsson Jacobi، نويسنده , , Mats Nordahl، نويسنده ,

  • Issue Information
    دوماهنامه با شماره پیاپی سال 2006
  • Pages
    7
  • From page
    479
  • To page
    485
  • Abstract
    Recombination is introduced into Eigenʹs theory of quasispecies evolution. Comparing numerical simulations of the rate equations in the non-recombining and recombining cases show that recombination has a strong effect on the error threshold and, for a wide range of mutation rates, gives rise to two stable fixed points in the dynamics. This bi-stability results in the existence of two error thresholds. However, we prove that, for low mutation rates the bi-stability breaks down and the unique equilibrium distribution is concentrated around the sequence with highest fitness
  • Keywords
    Crossover , quasispecies , recombination
  • Journal title
    Theoretical Population Biology
  • Serial Year
    2006
  • Journal title
    Theoretical Population Biology
  • Record number

    773946