• Title of article

    Theoretical description of chromosome architecture after multiple back-crossing

  • Author/Authors

    François Rodolphe، نويسنده , , Juliette Martin، نويسنده , , Emmanuelle Della-Chiesa، نويسنده ,

  • Issue Information
    دوماهنامه با شماره پیاپی سال 2008
  • Pages
    11
  • From page
    289
  • To page
    299
  • Abstract
    This paper provides a theoretical description of the chromosome architecture resulting from a given number of generations in a back-cross. It is worth considering chromosome architecture as being dependent on a marked point process, whose properties themselves depend on the crossing-over model used. The resulting architecture is presented here for two different models, one without interference, the other with complete interference. Exact distributions, with easy-to-compute formulae, are derived for quantities of interest, as the lengths of donor or receiver fragments, for any chromosome length and for both crossing-over models. Examples are presented to illustrate the use of these distributions in introgression programs
  • Keywords
    back-cross , Ehrenfest promenade , Crossing-over , interference , Poisson process , introgression
  • Journal title
    Theoretical Population Biology
  • Serial Year
    2008
  • Journal title
    Theoretical Population Biology
  • Record number

    774061