Title of article
Theoretical description of chromosome architecture after multiple back-crossing
Author/Authors
François Rodolphe، نويسنده , , Juliette Martin، نويسنده , , Emmanuelle Della-Chiesa، نويسنده ,
Issue Information
دوماهنامه با شماره پیاپی سال 2008
Pages
11
From page
289
To page
299
Abstract
This paper provides a theoretical description of the chromosome architecture resulting from a given number of generations in a back-cross. It is worth considering chromosome architecture as being dependent on a marked point process, whose properties themselves depend on the crossing-over model used. The resulting architecture is presented here for two different models, one without interference, the other with complete interference. Exact distributions, with easy-to-compute formulae, are derived for quantities of interest, as the lengths of donor or receiver fragments, for any chromosome length and for both crossing-over models. Examples are presented to illustrate the use of these distributions in introgression programs
Keywords
back-cross , Ehrenfest promenade , Crossing-over , interference , Poisson process , introgression
Journal title
Theoretical Population Biology
Serial Year
2008
Journal title
Theoretical Population Biology
Record number
774061
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