Title of article :
Can one learn history from the allelic spectrum?
Author/Authors :
Simon Myers، نويسنده , , Charles Fefferman، نويسنده , , Nick Patterson، نويسنده ,
Issue Information :
دوماهنامه با شماره پیاپی سال 2008
Pages :
7
From page :
342
To page :
348
Abstract :
It is well known that the neutral allelic frequency spectrum of a population is affected by the history of population size. A number of authors have used this fact to infer history given observed allele frequency data. We ask whether perfect information concerning the spectrum allows precise recovery of the history, and with an explicit example show that the answer is in the negative. This implies some limitations on how informative allelic spectra can be.
Keywords :
Diffusions , Allelic spectrum , Kimura
Journal title :
Theoretical Population Biology
Serial Year :
2008
Journal title :
Theoretical Population Biology
Record number :
774067
Link To Document :
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