Title of article
Detection of intersubtype recombinants with respect to env and nef genes of HIV-1 among female sex workers in Calcutta, India
Author/Authors
Payel Bhanja، نويسنده , , Satarupa Sengupta، نويسنده , , Debjani Banerjee، نويسنده , , Kamalesh Sarkar، نويسنده , , Smarajit Jana، نويسنده , , Sekhar Chakrabarti، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
5
From page
310
To page
314
Abstract
HIV-1 detected among female sex workers in Calcutta, India was characterized in respect to env and nef genes. A total of 39 HIV-1 seropositive samples were used in the study. Phylogenetic analysis of the nucleotide sequences of respective regions showed that 22 out of 39 samples (56.4%) were infected with subtype C with respect to both env and nef genes; however, 17 samples (43.6%) showed distinct subtype discordance. Simplot analysis of these samples showed the presence of intersubtype recombination between subtypes C and B. Both env C/nef B and env B/nef C recombinants were found to be present; 16 samples were found to be env C/nef B and 1 sample was detected as env B/nef C. This result indicates the emergence of intersubtype recombinants of HIV-1 for the first time in this eastern part of India.
Keywords
Phylogenetic tree , Intersubtype recombinants , sequence analysis
Journal title
Virus Research
Serial Year
2007
Journal title
Virus Research
Record number
786699
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