Title of article
Design and synthesis of nonpeptidal endothelin receptor antagonists based on the structure of a cyclic pentapeptide
Author/Authors
Natesan Murugesan، نويسنده , , Zhengxiang Gu، نويسنده , , Ving Lee، نويسنده , , Maria L. Webb، نويسنده , , Eddie C. -K. Liu، نويسنده , , Mark Hermsmeier، نويسنده , , John T. Hunt، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1995
Pages
6
From page
253
To page
258
Abstract
A series of dibenzodiazepine-10-acetic acid derivatives were synthesized as prototypes to mimic the structural features of the cyclopentapeptide endothelin antagonist 1. Some of the analogs showed moderate affinity for both the ETA and ETB receptors.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1995
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787319
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