Title of article :
Structure activity relationships of non-peptide bradykinin B2 receptor antagonists
Author/Authors :
Joseph M. Salvino، نويسنده , , Peter R. Seoane، نويسنده , , Brent D. Douty، نويسنده , , Mohamed A. Awad، نويسنده , , Denton Hoyer، نويسنده , , Tina Morgan Ross، نويسنده , , Roland E. Dolle، نويسنده , , Wayne T. Houck، نويسنده , , David M. Faunce، نويسنده , , David G. Sawutz، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1995
Pages :
6
From page :
357
To page :
362
Abstract :
A series of non-peptide competitive antagonists of the human IMR 90 fetal lung fibroblast bradykinin B2 receptor have been designed and synthesized. Compound 15 binds with an affinity constant Ki = 60 nM. The SAR leading to the design of these non-peptide antagonists is described.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
1995
Journal title :
Bioorganic & Medicinal Chemistry Letters
Record number :
787336
Link To Document :
https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=787336
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