Title of article :
Structure-activity studies of the natural product substance P antagonist win 64821
Author/Authors :
Colin J. Barrow، نويسنده , , Laszlo L. Musza، نويسنده , , Raymond Cooper، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1995
Abstract :
Tryptophyl alkylation at C3a of the diketopiperazine 2 gave compounds related to the substance P antagonist WIN 64821 (1). The biological activities of these compounds, and those of methyl analogs 13 and 14 produced by directed biosynthesis, gives structure-activity information for 1.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters