• Title of article

    Tritylated oncolytics as prodrugs

  • Author/Authors

    Vinod F. Patel، نويسنده , , Julie N. Hardin، نويسنده , , Gerald B. Grindey، نويسنده , , Richard M. Schultz، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1995
  • Pages
    6
  • From page
    513
  • To page
    518
  • Abstract
    A series of tritylated difluorodeoxynucleosides represent novel prodrugs in which there exists a predictable correlation between the electronic nature of the aromatic substituents on the trityl moiety and the acid mediated dissociation to free drug in ex vivo, in vitro and in vivo systems.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1995
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    787364