Title of article
Design and synthesis of an antitumor prodrug released by the reaction with sulfhydryl compounds
Author/Authors
Takao Izawa، نويسنده , , Kuniki Kato، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1995
Pages
4
From page
593
To page
596
Abstract
The design and synthesis of carbamate-daunomycin prodrug 11 that can release free daunomycin by the reaction with sulfhydryl compounds is described. The compound 11 is more sensitive to adriamycinresistant L1210 cell line than free daunomycin with relative resistance of 3.7 and 9.2, respectively.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1995
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787380
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