Title of article
Molecular design of novel PGI2 agonists without PG skeleton. I
Author/Authors
Nobuyuki Hamanaka، نويسنده , , Kanji Takahashi، نويسنده , , Yuuki Nagao، نويسنده , , Kazuhiko Torisu، نويسنده , , Hidekado Tokumoto، نويسنده , , Kigen Kondo، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1995
Pages
6
From page
1065
To page
1070
Abstract
Syntheses of novel prostaglandin (PG) mimetics without PG skeleton are described, and the structure-activity relationships are discussed. Highly potent compounds could be obtained when the PG analog 3 was modified by removing and reconstructing the cyclopentane ring, and changing the allylic alcohol in the natural PGs.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1995
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787470
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