Title of article
Molecular design of novel PGI2 agonists without PG skeleton. IV
Author/Authors
Nobuyuki Hamanaka، نويسنده , , Kanji Takahashi، نويسنده , , Yuuki Nagao، نويسنده , , Kazuhiko Torisu، نويسنده , , Hidekado Tokumoto، نويسنده , , Kigen Kondo، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1995
Pages
4
From page
1083
To page
1086
Abstract
The synthesis and biological evaluation of a novel series of di or tetrahydronaphthalene-5-oxyacetic acid derivatives with the 4-benzhydryl pyrazole group is described. Among these compounds, 7 has been identified as a highly potent PGI2 agonist with an exceptionally long in vivo duration of action.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1995
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787473
Link To Document