• Title of article

    Octahydro-1,2,3,4,4a,5,11,11a-pyrido[3,4-c][1,5]benzoxazepines: conformationally restricted fentanyl analogs

  • Author/Authors

    Linas V. Kudzma، نويسنده , , Suzanne M. Evans، نويسنده , , Stanhope P. Turnbull Jr.، نويسنده , , Sherry A. Severnak، نويسنده , , Edward F. Ezell، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1995
  • Pages
    6
  • From page
    1177
  • To page
    1182
  • Abstract
    Synthesis, analgesic activity and preliminary molecular modeling studies of the cis- and trans-fused octahydro-1,2,3,4,4a,5,11,11a-pyrido[3,4-c][1,5]benzoxazepines8 and 9, the first rigid fentanyl analogs with a conformationally restricted 4-anilido group that retain antinociceptive properties, are reported.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1995
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    787492