Quinuclidine-based NK1 antagonists, the role of the benzhydryl
Author/Authors :
C. J. Swain، نويسنده , , T. M. Fong، نويسنده , , K. Haworth، نويسنده , , S. N. Owen، نويسنده , , E. M. Seward، نويسنده , , C. D. Strader، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1995
Pages :
4
From page :
1261
To page :
1264
Abstract :
Initial work on a series of quinuclidine based antagonists suggested that only one of the rigns of the benzhydryl was involved in receptor binding. This communication endeavors to test this hypothesis and to identify which of the phenyl rings interacts with Histidine 197.
