Title of article
(3R, 4S)-3-Benzyl-4-bromomethyloxetan-2-one, a fast acting alternate substrate inhibitor of α-chymotrypsin
Author/Authors
Dong H. Kim and Seiichi Shin ، نويسنده , , Jae Jeong Ryoo، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1995
Pages
6
From page
1287
To page
1292
Abstract
(3R,4S)-3-Benzyl-4-(bromomethyl)oxetan-2-one is a novel type of fast acting alternate substrate inhibitor for α-chymotrypsin. The hydroxyl group that is generated during the turnover process appears to be responsible for the high stability of the acyl enzyme intermediate.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1995
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787512
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