Title of article
Synthesis of the macrolide antibiotic, oxolide
Author/Authors
Brian A. Roden، نويسنده , , Sanjay Chemburkar، نويسنده , , Leslie Freiberg(dec.)، نويسنده , , Yi-Yin Ku، نويسنده , , Richard Pariza، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1995
Pages
4
From page
1307
To page
1310
Abstract
Oxolide was synthesized from Erythromycin A. Key features include two stereoselective reductions with DIBALH and NaBH3CN and a novel pH dependent purification of the final product.
Abstract
An acid-stable macrolide, oxolide, was synthesized from Erythromycin A. Key features include two stereoselective reductions with DIBALH and NaBH3CN and a simple pH dependent separation of the final product from its C-11 epimer.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1995
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787516
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