Title of article :
Synthesis of the macrolide antibiotic, oxolide
Author/Authors :
Brian A. Roden، نويسنده , , Sanjay Chemburkar، نويسنده , , Leslie Freiberg(dec.)، نويسنده , , Yi-Yin Ku، نويسنده , , Richard Pariza، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1995
Abstract :
Oxolide was synthesized from Erythromycin A. Key features include two stereoselective reductions with DIBALH and NaBH3CN and a novel pH dependent purification of the final product.
Abstract
An acid-stable macrolide, oxolide, was synthesized from Erythromycin A. Key features include two stereoselective reductions with DIBALH and NaBH3CN and a simple pH dependent separation of the final product from its C-11 epimer.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
