Title of article
Synthesis of thymidine dimers containing a new internucleosidic amide linkage and their incorporation into oligodeoxyribonucleotides
Author/Authors
L. De Napoli، نويسنده , , A. Iadonisi، نويسنده , , D. Montesarchio، نويسنده , , M. Varra، نويسنده , , G. Piccialli، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1995
Pages
6
From page
1647
To page
1652
Abstract
The synthesis of thymidine dimers 5a,b containing a chiral carbon in the propionamide internucleosidic linkage is described. These new epimeric dimers were incorporated in oligodeoxyribonucleotides and the melting temperature (Tm) with complementary DNA and RNA as well as the resistence of the single strand against exonuclease were determined.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1995
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787577
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