• Title of article

    9-Aminoacridine-EDTA conjugates as hydroxy radical footprinting reagents with no intrinsic cutting specificity

  • Author/Authors

    Francis C. K. Chiu، نويسنده , , Robert T. C. Brownlee، نويسنده , , Kirsten Mitchell، نويسنده , , Don R. Phillips، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1995
  • Pages
    6
  • From page
    1689
  • To page
    1694
  • Abstract
    9-Aminoacridine-EDTA conjugates were prepared as DNA footprinting reagents in conjunction with ferrous ion. The complexes were found to have no significant DNA cutting preferences and are more effective than free EDTA. The application was demonstrated with the footprinting of the lac repressor bound specifically to the lac operon.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1995
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    787585

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=787585