Title of article
N-(1-phenyl-2-benzimidazolyl)-N′-phenylurea derivatives as potent in hibitors of acylcoa:cholesterol acyltransferase (ACAT)
Author/Authors
Toshiaki Kumazawa، نويسنده , , Hiroyuki Harakawa، نويسنده , , Hiromi Fukui، نويسنده , , Shiro Shirakura، نويسنده , , Eiko Ohishi، نويسنده , , Koji Yamada، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1995
Pages
4
From page
1829
To page
1832
Abstract
A novel series of N-(1-phenyl-2-benzimidazolyl)-N′-phenylurea derivatives were prepared as ACAT inhibitors. These compounds showed potent ACAT inhibitory activity in vitro (liver microsomes from cholesterol-fed rabbits) and hypocholesterolemic activity in vivo (cholesterol-fed golden hamsters).
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1995
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787608
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