Author/Authors :
Migyoung Lee، نويسنده , , Chung K. Chu، نويسنده , , S. Balakrishna Pai، نويسنده , , Yong-Lian Zhu and، نويسنده , , Yung-Chi Cheng، نويسنده , , Moon Woo Chun and، نويسنده , , Won Keun Chung، نويسنده ,
Abstract :
In order to study the structure-activity relationships, several dioxolane pyrimidine nucleosides have been synthesized and their anti-HBV activities have been evaluated in 2.2.15 cells. From the study it was found that 5-fluoro-cytosine derivatives exhibited the most potent anti-HBV activity.
