• Title of article

    A new deprotection strategy for automated oligonucleotide synthesis using a novel silyl-linked solid support

  • Author/Authors

    Anne Routledge، نويسنده , , Mark P. Wallis، نويسنده , , Kenneth C. Ross، نويسنده , , William Fraser، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1995
  • Pages
    6
  • From page
    2059
  • To page
    2064
  • Abstract
    Automated solid phase synthesis of 2′-deoxyribose oligonucleotides; d(Tp)7T, d(Tps)7T and d(Tp)3(CBzp)2(Tp)2T, was achieved directly in 99% overall yields using a novel silyl linkage to a CPG silica support cleavable within seconds at room temperature using TBAF.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1995
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    787652