• Title of article

    Convergent approach to water soluble camptothecin derivatives

  • Author/Authors

    Zhuo-Feng Xie، نويسنده , , Koichiro Ootsu، نويسنده , , Hiroshi Akimoto، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1995
  • Pages
    6
  • From page
    2189
  • To page
    2194
  • Abstract
    New water soluble camptothecin derivatives with excellent antitumor activity have been designed and synthesized. The synthetic approach includes an efficient route to 7-aminoethyl and 7-aminomethyl camptothecins using either N-Boc protected aminopropion(or aceto)aldehyde or N-methylacetamide as alkylating agents.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1995
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    787678