Title of article
Enzymatic cyclization of nicotinamide adenine dinucleotide phosphate (NADP)
Author/Authors
Fang-Jie Zhang، نويسنده , , Qu-Ming Gu، نويسنده , , Peicheng Jing، نويسنده , , Charles J. Sih، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1995
Pages
6
From page
2267
To page
2272
Abstract
The ADP-ribosyl cyclase of Aplysia californica catalyzed the conversion of NADP, 3′-NADP and 2′,3′-cyclic NADP into their corresponding cyclic nucleotides (established by NMR, UV, and MS analyses). Cyclic-ADP-ribose-phosphate (cADPRP) was more potent than cADPR in mobilizing calcium in the rat brain microsomal system; the EC50 for cADPRP and cADPR were 9.2 μM and 22 μM respectively.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1995
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787694
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