Author/Authors :
Shigeru Nishiyama، نويسنده , , Yoshiko Kikuchi، نويسنده , , Hiroko Kurata، نويسنده , , Shosuke Yamamura، نويسنده , , Takao Izawa، نويسنده , , Takemitsu Nagahata، نويسنده , , Ryuji Ikeda، نويسنده , , Kuniki Kato، نويسنده ,
Abstract :
The enantiomerically pure synthesis of [(2′S, 3′S)-bis(hydroxymethyl)azetidin-1-yl] adenine 9 and -guanine 13 was achieved via construction of the base on the 1-amino-azetidine 4 and their anti-HSV-1 and -2, and anti-HIV-1 activities were evaluated.
