Versatile synthetic routes to threo-β-amino hydroxy carboxylic acids, statine and its analogues

Efficient syntheses of statine and its analogues have been attained from aziridine diols 3 and ent-3, which were prepared via iodocyclization of trichloroacetimidates of chiral 3-buten-1,2-diols 1 and ent-1.