Title of article
Thromboxane modulating agents. 1. Design of 1-[(arylsulfonyl)amino] alkylindole derivatives as dual thromboxane synthase inhibitor/thromboxane receptor antagonists.
Author/Authors
Roger P. Dickinson، نويسنده , , Kevin N. Dack، نويسنده , , John Steele، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1995
Pages
6
From page
3017
To page
3022
Abstract
The design of a series of dual thromboxane synthase inhibitor/thromboxane receptor antagonists based on an indole thromboxane synthase inhibitor template is described. The indole-5-propanoic acid derivatives 17, 22 and 23 were found to be potent dual agents in vitro.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1995
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787828
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