Title of article :
Enantiodifferentiation of dihydropyridine PAF antagonists
Author/Authors :
Kelvin Cooper، نويسنده , , M. Jonathan Fray، نويسنده , , M. John Parry، نويسنده , , Kenneth Richardson، نويسنده , , John Steele، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1995
Abstract :
The PAF antagonist activity of a series of enantiomeric dihydropyridines is described. In the first example, 1, the PAF antagonist activity and calcium channel blocking activity reside in opposite enantiomers. Subsequent examples also display enantioselectivity and the SAR of the series is described.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters