Title of article
Molecular shape analysis and activity of tautomycin, a protein phosphatase inhibitor
Author/Authors
Yukiteru Sugiyama، نويسنده , , Ikuko I. Ohtani، نويسنده , , Minoru Isobe and Kunio Miki، نويسنده , , Akira Takai، نويسنده , , Makoto Ubukata، نويسنده , , Kiyoshi Isono، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
6
From page
3
To page
8
Abstract
Tautomycin, a well-known protein phosphatase inhibitor, exists in two forms (acid anhydride and diacid). We successfully isolated them and proved that diacid is the real active form of tautomycin. The molecular shape-activity relationship of tautomycin and its conformational analysis are also described.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787845
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