• Title of article

    A facile synthesis of 2-azidoadenosine derivatives from guanosine as photoaffinity probes

  • Author/Authors

    Seiichiro Higashiya، نويسنده , , Chitose Kaibara، نويسنده , , Koichiro Fukuoka، نويسنده , , Fuminori Suda، نويسنده , , Masahide Ishikawa، نويسنده , , Masasuke Yoshida، نويسنده , , Tsujiaki Hata، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1996
  • Pages
    4
  • From page
    39
  • To page
    42
  • Abstract
    2-Azidoadenosine (1) was synthesized in an overall yield of 49% from guanosine via the reaction of 9-(2′,3′,5′-tri-O-acetyl-β-D-ribofuranosyl)-2-amino-6-chloropurine (2) with isoamyl nitrite and trimethylsilyl azide under neutral and anhydrous conditions. As photoaffinity probes, ATP analogues and the cap structure of eukaryotic mRNA bearing 2-azidoadenosine were synthesized
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1996
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    787852