Title of article
Catechol based inhibitors of 15-lipoxygenase
Author/Authors
Bradley D. Tait، نويسنده , , Richard D. Dyer، نويسنده , , Bruce J. Auerbach، نويسنده , , Dirk Bornemeier، نويسنده , , Linda Guilds-Zamarka، نويسنده , , Maritza Oxender، نويسنده , , Bruce D. Roth، نويسنده , , Bharat K. Trivedi، نويسنده , , Joseph A. Cornicelli، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
4
From page
93
To page
96
Abstract
A potent 15-lipoxygenase (15-LO) inhibitor, compound 6, was identified by mass screening the Parke-Davis compound portfolio. The active moiety of compound 6 was determined to be the catechol functionality. Additional analogs were prepared and analyzed for inhibitory activity against 5-, 12-, and 15- lipoxygenase.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787863
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